Isopropanol →

HRID 2418671Notes

Reaction equation

HRID 2418671 reaction equation
[CH2:1]([P:3]([Cl:6])([Cl:5])=[S:4])[CH3:2].[CH:7](O)([CH3:9])[CH3:8].C(N(CC)CC)C>C1C=CC=CC=1>[CH2:1]([P:3]([ClH:6][CH:7]([CH3:9])[CH3:8])([Cl:5])=[S:4])[CH3:2]

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 8471TriethylamineHCID 61246ethyl phosphonothioic dichloride, anhydrous

Product 0

No Product data yet.

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To a stirred mixture of 74.2 g (0.455 moles) ##STR16## ethylphosphonothioic dichloride in 400 ml benzene, 30.1 g (0.5 moles) isopropyl alcohol was added. To that mixture 50.6 g (0.5 moles) triethylamine was added at a dropwise rate overnight. The mixture was then warmed for about 1 hour. The mixture was filtered by gravity. Most of the solvent (benzene) was stripped off under reduced pressure and heat to give ethyl-O-isopropylphosphonothioic chloride: ##STR17##

Workup

  1. additionwas added
  2. temperatureThe mixture was then warmed for about 1 hour
  3. filtrationThe mixture was filtered by gravity
  4. temperatureheat

Sources & evidence

ORD record
ord-da14968379104f88af4aa798255b5c95
Source dataset
uspto-grants-1984_09
Patent number
US04473562

Reaction notes

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