Lactate → Nadide (JAN/USAN/INN)

HRID 247008

Reaction equation

HRID 247008 reaction equation
[CH:1]1[N:2]=[C:3]([NH2:44])[C:4]2[N:9]=[CH:8][N:7]([C@@H:10]3[O:14][C@H:13]([CH2:15][O:16][P:17]([O:20][P:21]([O:24][CH2:25][C@H:26]4[O:30][C@@H:29]([N:31]5[CH:36]=[C:35]([C:37]([NH2:39])=[O:38])[CH2:34][CH:33]=[CH:32]5)[C@H:28]([OH:40])[C@@H:27]4[OH:41])([OH:23])=[O:22])([OH:19])=[O:18])[C@@H:12]([OH:42])[C@H:11]3[OH:43])[C:5]=2[N:6]=1.[C:45]([O-:50])(=[O:49])[CH:46]([CH3:48])[OH:47]>>[C:45]([O-:50])(=[O:49])[CH:46]([CH3:48])[OH:47].[CH:33]1[CH:32]=[N+:31]([C@@H:29]2[O:30][C@H:26]([CH2:25][O:24][P:21]([O:20][P:17]([O:16][CH2:15][C@H:13]3[O:14][C@@H:10]([N:7]4[C:5]5[N:6]=[CH:1][N:2]=[C:3]([NH2:44])[C:4]=5[N:9]=[CH:8]4)[C@H:11]([OH:43])[C@@H:12]3[OH:42])([OH:19])=[O:18])([OH:23])=[O:22])[C@@H:27]([OH:41])[C@H:28]2[OH:40])[CH:36]=[C:35]([C:37]([NH2:39])=[O:38])[CH:34]=1

Participants

4

Reactant 2

HCID 91435LactateHCID 439153Nadh

Product 2

HCID 5893Nadide (JAN/USAN/INN)HCID 91435Lactate

Procedure

In the case of this determination, ADP is reacted with phosphoenol pyruvate (PEP) in the presence of pyruvate kinase (PK) to give pyruvate which, in turn, is reacted with NADH in the presence of lactate dehydrogenase (LDH) to give lactate and NAD+.

Sources & evidence

ORD record
ord-ef59350ea5c44018ad6e72e58e663dac
Source dataset
uspto-grants-1987_11
Patent number
US04705749

Linked notes

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