Hydrochloric Acid → Hydroxylamine

HRID 258746

Reaction equation

HRID 258746 reaction equation
[CH3:1][NH:2][C:3]([NH:5][CH2:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[NH:15][CH:14]=[N:13][C:12]=1[CH3:16])=[S:4].[ClH:17].Cl.Cl.[OH:20][NH:21][C:22]([NH:34]C)=[N:23][CH2:24][CH2:25][S:26][CH2:27][C:28]1[NH:32][CH:31]=[N:30][C:29]=1[CH3:33]>>[ClH:17].[ClH:17].[CH3:1][NH:2][C:3](=[N:5][CH2:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[NH:15][CH:14]=[N:13][C:12]=1[CH3:16])[S:4][CH3:22].[NH2:21][OH:20].[ClH:17].[ClH:17].[ClH:17].[OH:20][N:21]([CH2:7][CH2:8][S:9][CH2:10][C:11]1[NH:15][CH:14]=[N:13][C:12]=1[CH3:16])[C:22]([NH2:34])=[N:23][CH2:24][CH2:25][S:26][CH2:27][C:28]1[NH:32][CH:31]=[N:30][C:29]=1[CH3:33]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 178485010HCID 178485010, compoundHCID 178486113HCID 178486113, compound

Product 3

HCID 787HydroxylamineHCID 178433318HCID 178433318, compoundHCID 178484968HCID 178484968, compound

Procedure

Reaction of N-methyl-N'-[3-((4-methyl-5-imidazolyl)methylthio)propyl]thiourea with methanolic hydrogen chloride by the method of Example 1 (i) yielded N,S-dimethyl-N'-[3-((4-methyl-5-imidazolyl)methylthio)propyl]isothiourea dihydrochloride which on treatment with hydroxylamine by the procedure of Example 1 (ii) gave the title product.

Sources & evidence

ORD record
ord-e5077c1e46cf40869e76d5de8eaa8d3a
Source dataset
uspto-grants-1977_07
Patent number
US04034101

Linked notes

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