Hydroxyamine hydrochloride → 1-Hydroxy-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea
Reaction equation
[S:1]1[CH:5]=[CH:4][C:3]2[CH:6]([N:10]=[C:11]=[O:12])[CH2:7][CH2:8][CH2:9][C:2]1=2.Cl.[NH2:14][OH:15]>C(N(CC)CC)C>[OH:15][NH:14][C:11]([NH:10][CH:6]1[C:3]2[CH:4]=[CH:5][S:1][C:2]=2[CH2:9][CH2:8][CH2:7]1)=[O:12]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The above compound is prepared in the manner described in Example 6, by allowing 4,5,6,7-tetrahydrobenzo-[b]thien-4-yl isocyanate to react with hydroxylamine hydrochloride in the presence of triethylamine. The product melts at 158.5° C. to 160.5° C.
Workup
- customThe above compound is prepared in the manner
Sources & evidence
- ORD record
- ord-273acd3a982b4be3a22c0dbe7e941c34
- Source dataset
- uspto-grants-1977_07
- Patent number
- US04036979
Reaction notes
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