Tetraethylene Glycol → Heptaethylene glycol

HRID 263282

Reaction equation

HRID 263282 reaction equation
[Na].[CH2:2]([OH:14])[CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][OH:13].C1(S(O[CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][OH:33])(=O)=O)C=CC=CC=1.C1C=CC=CC=1.[Na]>>[CH2:12]([OH:13])[CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2][O:14][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH2:31][CH2:32][OH:33]

Participants

5

Reactant 4

HCID 8200Tetraethylene GlycolHCID 5360545SodiumHCID 213163252-(2-(2-Hydroxyethoxy)ethoxy)ethyl benzenesulfonateHCID 66691470Sodium benzene

Product 1

HCID 79718Heptaethylene glycol

Procedure

Dissolve one equivalet of sodium in at least 5 equivalents of tetraethylene glycol and then add one equivalent of triethylene glycol monobenzenesulfonate. Heat the resulting solution at 100° to 150° C. until the elimination of sodium benzene sulfontate is substantially complete. Remove the insoluble sulfonate salt by filtration and fractionally distill the resultiing product in vacuo to obtain heptaethylene glycol as the higher boiling fraction.

Workup

  1. customRemove the insoluble sulfonate salt
  2. filtrationby filtration
  3. distillationfractionally distill the resultiing product in vacuo

Sources & evidence

ORD record
ord-89a88e341248424db66adbb8ba5c6985
Source dataset
uspto-grants-1979_05
Patent number
US04156683

Linked notes

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