Hydrochloric Acid → HCID 14631382, compound
Reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH:6](O)[CH3:7].[CH2:9]=[O:10].[Cl-:11].[Ca+2].[Cl-].Cl>C(Cl)Cl>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:10][CH2:9][Cl:11]Participants
6
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH:6](O)[CH3:7].[CH2:9]=[O:10].[Cl-:11].[Ca+2].[Cl-].Cl>C(Cl)Cl>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:10][CH2:9][Cl:11]Hydrogen chloride gas was bubbled into a mixture containing 24 g (200 mmol) of (2-methoxyethoxy)ethanol, 6.0 g (200 mmol) of paraformaldehyde and 22 g (200 mmol) of powdered calcium chloride with stirring and cooling to -5° C. The HCl was continued for 4 hours as the temperature was allowed to rise gradually to 8° C. Celite was added and the reaction filtered. The filtrate was evaporated leaving 29.8 g of a cloudy oil. The oil was dissolved in methylene chloride and dried over molecular sieves. Evaporation furnished 19.3 g of [2-(2-methoxyethoxy)ethoxy]methyl chloride as an oil which was characterized by nuclear magnetic resonance.
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