M-Cresol → 2,4,6-Trimethylphenol

HRID 280723

Reaction equation

HRID 280723 reaction equation
C1C(O)=CC=CC=1C.C1C(O)=CC=C(C)C=1.C[O:18][CH3:19].[CH3:20][C:21]1[C:26](C)=[CH:25][CH:24]=[C:23]([CH3:28])[C:22]=1O>CO>[CH3:24][C:25]1[CH:26]=[C:21]([CH3:20])[CH:22]=[C:23]([CH3:28])[C:19]=1[OH:18]

Participants

6

Reactant 4

HCID 342M-Cresol2×HCID 2879P-Cresol2×HCID 8254Dimethyl EtherHCID 170162,3,6-Trimethylphenol

Product 1

HCID 106982,4,6-Trimethylphenol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

methylating meta-cresol and para-cresol in the ortho position by reacting the meta-cresol and para-cresol with methanol, dimethyl ether or a mixture thereof at a temperature of 270° to 450° C., at a pressure of atmospheric to 100 bar and in the presence of a catalyst bed without a residence time of 0.01 to 10 seconds, whereby a mixture of 2,3,6-trimethylphenol and 2,4,6-trimethylphenol is produced;

Sources & evidence

ORD record
ord-1fec35ca492647bfab2337bac42a837c
Source dataset
uspto-grants-1986_05
Patent number
US04590306

Linked notes

Loading…