M-Cresol → 2,4,6-Trimethylphenol
Reaction equation
C1C(O)=CC=CC=1C.C1C(O)=CC=C(C)C=1.C[O:18][CH3:19].[CH3:20][C:21]1[C:26](C)=[CH:25][CH:24]=[C:23]([CH3:28])[C:22]=1O>CO>[CH3:24][C:25]1[CH:26]=[C:21]([CH3:20])[CH:22]=[C:23]([CH3:28])[C:19]=1[OH:18]Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
methylating meta-cresol and para-cresol in the ortho position by reacting the meta-cresol and para-cresol with methanol, dimethyl ether or a mixture thereof at a temperature of 270° to 450° C., at a pressure of atmospheric to 100 bar and in the presence of a catalyst bed without a residence time of 0.01 to 10 seconds, whereby a mixture of 2,3,6-trimethylphenol and 2,4,6-trimethylphenol is produced;
Sources & evidence
- ORD record
- ord-1fec35ca492647bfab2337bac42a837c
- Source dataset
- uspto-grants-1986_05
- Patent number
- US04590306
Reaction notes
Loading…