Dichloromethane → 17-Ethyl-1-hydroxy-14-(tert-butyldimethylsiloxy)-12-[2'-(4"-allyloxy-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraone

HRID 281208

Reaction equation

HRID 281208 reaction equation
[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:63])[CH2:5][CH:6]([O:55][Si:56]([CH3:57])([CH3:58])[C:59]([CH3:60])([CH3:61])[CH3:62])[CH:7]([CH3:54])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:51][CH3:52])[CH:47]([OH:50])[CH2:48][CH2:49]2)[CH3:53])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2.[CH2:82]([Cl:83])[Cl:84].[CH2:85]1[CH2:86][CH2:87][CH2:88][CH2:89][CH2:90]1.[CH3:91][CH2:92][O:93][C:94](=[O:95])[CH3:96].[Cl:64][C:65]([Cl:66])([Cl:67])[C:71](=[NH:72])[O:73][CH2:68][CH:69]=[CH2:70].[OH:74][S:75]([C:76]([F:77])([F:78])[F:79])(=[O:80])=[O:81]>>[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:63])[CH2:5][CH:6]([O:55][Si:56]([CH3:57])([CH3:58])[C:59]([CH3:60])([CH3:61])[CH3:62])[CH:7]([CH3:54])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:51][CH3:52])[CH:47]([O:50][CH2:70][CH:69]=[CH2:68])[CH2:48][CH2:49]2)[CH3:53])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 8078CyclohexaneHCID 8857Ethyl AcetateHCID 62406Trifluoromethanesulfonic acidHCID 316905Allyl 2,2,2-TrichloroacetimidateHCID 5724677817-Ethyl-1-hydroxy-12-[2'-(4"-hydroxy-3"-methoxycyclohexyl)-1'-methylvinyl]-14-t-butyl-dimethylsilyloxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraone

Product 1

HCID 5711397117-Ethyl-1-hydroxy-14-(tert-butyldimethylsiloxy)-12-[2'-(4"-allyloxy-3"-methoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraone

Sources & evidence

ORD record
ord-5604a3f3dce442149d00806a4a5d0a59
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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