Ciprofloxacin → 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-{4-[2-oxo-1-(methoxycarbonyl)-1-propyl]-1-piperazinyl}-3-quinolinecarboxylic acid

HRID 283601

Reaction equation

HRID 283601 reaction equation
[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[CH:1]1([n:4]2[cH:5][c:6]([C:22](=[O:23])[OH:24])[c:7](=[O:21])[c:8]3[cH:9][c:10]([F:20])[c:11]([N:14]4[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]4)[cH:12][c:13]23)[CH2:2][CH2:3]1.[Cl:25][CH:26]([C:27](=[O:28])[O:29][CH3:30])[C:31](=[O:32])[CH3:33]>>[CH:1]1([n:4]2[cH:5][c:6]([C:22](=[O:23])[OH:24])[c:7](=[O:21])[c:8]3[cH:9][c:10]([F:20])[c:11]([N:14]4[CH2:15][CH2:16][N:17]([CH:26]([C:27](=[O:28])[O:29][CH3:30])[C:31](=[O:32])[CH3:33])[CH2:18][CH2:19]4)[cH:12][c:13]23)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 2764CiprofloxacinHCID 6228DimethylformamideHCID 8471TriethylamineHCID 107332Methyl 2-chloroacetoacetate

Product 1

HCID 133379311-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-{4-[2-oxo-1-(methoxycarbonyl)-1-propyl]-1-piperazinyl}-3-quinolinecarboxylic acid

Sources & evidence

ORD record
ord-209a7e8ae9de4de681244cc0fac506c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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