Tetrahydrofuran → 1-(3-(2-Cyanopropan-2-yl)phenyl)-3-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea

Reaction equation

[C:23](#[N:24])[C:25]([CH3:26])([CH3:27])[c:28]1[cH:29][c:30]([NH:34][C:35]([O:36][c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)=[O:37])[cH:31][cH:32][cH:33]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:49][N:50]([c:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1)[CH3:57]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH:19][C:35]([NH:34][c:30]4[cH:29][c:28]([C:25]([C:23]#[N:24])([CH3:26])[CH3:27])[cH:33][cH:32][cH:31]4)=[O:36])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]