Benzene → Ethyl 3-(2-fluoro-4-biphenylyl)-2-butenoate

HRID 286001

Reaction equation

HRID 286001 reaction equation
[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([F:16])[c:7](-[c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:8][cH:9]1.[CH2:17]([CH3:18])[O:19][C:20]([CH2:21][Br:22])=[O:23].[Cl:25][P:26]([Cl:27])[Cl:28].[ClH:24].[OH2:36].[Zn:35].[cH:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[C:1]([CH3:2])([c:4]1[cH:5][c:6]([F:16])[c:7](-[c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[cH:8][cH:9]1)=[CH:21][C:20]([O:19][CH2:17][CH3:18])=[O:23]

Participants

8

Reactant 7

HCID 241BenzeneHCID 313Hydrochloric AcidHCID 962WaterHCID 7748Ethyl bromoacetateHCID 23994ZincHCID 24387Phosphorus trichlorideHCID 64519181-(2-Fluoro(1,1'-biphenyl)-4-yl)ethan-1-one

Product 1

HCID 53797937Ethyl 3-(2-fluoro-4-biphenylyl)-2-butenoate

Sources & evidence

ORD record
ord-819fd8eb6b224ea0a375725c2119b822
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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