Piperazine → Methyl 3-fluoro-4-(piperazin-1-yl)benzoate

HRID 287890

Reaction equation

HRID 287890 reaction equation
[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[CH2:1]1[CH2:2][NH:3][CH2:4][CH2:5][NH:6]1.[F:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16][c:17]1[F:18]>>[CH2:1]1[CH2:2][N:3]([c:17]2[c:8]([F:7])[cH:9][c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][cH:16]2)[CH2:4][CH2:5][NH:6]1

Participants

4

Reactant 3

HCID 4837PiperazineHCID 8028TetrahydrofuranHCID 2775358Methyl 3,4-difluorobenzoate

Product 1

HCID 18425273Methyl 3-fluoro-4-(piperazin-1-yl)benzoate

Sources & evidence

ORD record
ord-cae0ccfa635049d69fa877a00ab1b888
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…