Hydrochloric Acid → Hydrochloric Acid

HRID 288448

Reaction equation

HRID 288448 reaction equation
[Br:1][c:2]1[c:3]([N:19]2[CH2:20][CH:21]([NH:25][C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:22][CH2:23][CH2:24]2)[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[CH2:15][O:16][CH2:17][CH2:18]1.[CH3:41][OH:42].[CH3:46][CH2:47][O:48][CH2:49][CH3:50].[Cl:43][CH2:44][Cl:45].[ClH:33].[F:34][C:35]([F:36])([F:37])[C:38]([OH:39])=[O:40]>>[Br:1][c:2]1[c:3]([N:19]2[CH2:20][CH:21]([NH2:25])[CH2:22][CH2:23][CH2:24]2)[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[CH2:15][O:16][CH2:17][CH2:18]1.[ClH:33]

Participants

8

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178452776HCID 178452776, compound

Product 2

HCID 313Hydrochloric AcidHCID 67045026N-[4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl]oxolane-3-carboxamide

Sources & evidence

ORD record
ord-b21c888b230c4587bad292878a5b779d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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