Tetrahydrofuran → 1-benzyl-N,4-dimethylpiperidin-3-amine

HRID 288584

Reaction equation

HRID 288584 reaction equation
[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:1][O:2][C:3]([NH:4][CH:5]1[CH2:6][N:7]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:8][CH2:9][CH:10]1[CH3:11])=[O:19].[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[CH3:3][NH:4][CH:5]1[CH2:6][N:7]([CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:8][CH2:9][CH:10]1[CH3:11]

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 53396489Methyl 1-benzyl-4-methylpiperidin-3-yl-carbamate

Product 1

HCID 99438891-benzyl-N,4-dimethylpiperidin-3-amine

Sources & evidence

ORD record
ord-587613a99072455494198bdf58d67098
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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