5-Fluorouracil → Butanoic acid, (5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl ester

HRID 289706

Reaction equation

HRID 289706 reaction equation
[C:17]([CH2:18][CH2:19][CH3:20])(=[O:21])[O:22][CH2:23][Cl:24].[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:25][N:26]([CH3:27])[CH:28]=[O:29].[F:1][c:2]1[c:3](=[O:9])[nH:4][c:5](=[O:8])[nH:6][cH:7]1>>[F:1][c:2]1[c:3](=[O:9])[nH:4][c:5](=[O:8])[n:6]([CH2:23][O:22][C:17]([CH2:18][CH2:19][CH3:20])=[O:21])[cH:7]1

Participants

5

Reactant 4

HCID 33855-FluorouracilHCID 6228DimethylformamideHCID 8471TriethylamineHCID 2725008Chloromethyl butanoate

Product 1

HCID 94621Butanoic acid, (5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl ester

Sources & evidence

ORD record
ord-f05a941e16794e3bbe696d5ec5597110
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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