Dimethyl Sulfoxide → N-imidazo[1,2-b]pyridazin-6-yl-4-(4-phenyl-1,3-thiazol-2-yl)piperazine-1-carboxamide

HRID 289920

Reaction equation

HRID 289920 reaction equation
[CH3:46][S:47]([CH3:48])=[O:49].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[CH:36]([N:37]([CH:38]([CH3:39])[CH3:40])[CH2:41][CH3:42])([CH3:43])[CH3:44].[OH2:45].[c:19]1(-[c:25]2[n:26][c:27]([N:30]3[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]3)[s:28][cH:29]2)[cH:20][cH:21][cH:22][cH:23][cH:24]1.[n:1]1[cH:2][cH:3][n:4]2[n:5][c:6]([NH:10][C:11]([O:12][CH2:13][C:14]([Cl:15])([Cl:16])[Cl:17])=[O:18])[cH:7][cH:8][c:9]12>>[n:1]1[cH:2][cH:3][n:4]2[n:5][c:6]([NH:10][C:11](=[O:18])[N:33]3[CH2:32][CH2:31][N:30]([c:27]4[n:26][c:25](-[c:19]5[cH:20][cH:21][cH:22][cH:23][cH:24]5)[cH:29][s:28]4)[CH2:35][CH2:34]3)[cH:7][cH:8][c:9]12

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 7124681-(4-Phenyl-1,3-thiazol-2-yl)piperazineHCID 687778772,2,2-Trichloroethyl imidazo[1,2-b]pyridazin-6-ylcarbamate

Product 1

HCID 68778080N-imidazo[1,2-b]pyridazin-6-yl-4-(4-phenyl-1,3-thiazol-2-yl)piperazine-1-carboxamide

Sources & evidence

ORD record
ord-b69d89559c064b57abb6bac2fedce0f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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