Dimethylformamide → 4-((4-chlorophenyl)-ethynyl)-1-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)pyridin-2(1H)-one

HRID 293338

Reaction equation

HRID 293338 reaction equation
[CH2:23]([Sn:24]([CH2:25][CH2:26][CH2:27][CH3:37])([C:28]#[C:29][c:30]1[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]1)[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[Cl:1][c:2]1[cH:3][c:4](=[O:22])[n:5](-[c:8]2[cH:9][c:10]([O:20][CH3:21])[c:11]([O:14][CH2:15][C:16]([CH3:17])([CH3:18])[OH:19])[cH:12][cH:13]2)[cH:6][cH:7]1.[Cl:50][CH2:51][Cl:52].[Cu:53][I:54].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[c:2]1([C:28]#[C:29][c:30]2[cH:31][cH:32][c:33]([Cl:36])[cH:34][cH:35]2)[cH:3][c:4](=[O:22])[n:5](-[c:8]2[cH:9][c:10]([O:20][CH3:21])[c:11]([O:14][CH2:15][C:16]([CH3:17])([CH3:18])[OH:19])[cH:12][cH:13]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 58580242Tributyl((4-chlorophenyl)ethynyl)stannaneHCID 585802944-chloro-1-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)pyridin-2(1H)-one

Product 1

HCID 469116644-((4-chlorophenyl)-ethynyl)-1-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-d78ef97facf744b898c50c36c4e552a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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