Tetrahydrofuran → 5-chloro-1-methyl-N-[3-[2-oxo-3-[[4-(2-pyrrolidin-1-ylethyl)anilino]methylidene]-1H-indole-6-carbonyl]phenyl]pyrazole-4-carboxamide

HRID 293387

Reaction equation

HRID 293387 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:50][CH2:51][O:52][C:53]([CH3:54])=[O:55].[CH3:56][CH2:57][CH2:58][CH2:59][CH2:60][CH3:61].[N:36]1([CH2:41][CH2:42][c:43]2[cH:44][cH:45][c:46]([NH2:49])[cH:47][cH:48]2)[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH:1][CH:2]=[C:3]1[C:4](=[O:30])[NH:5][c:6]2[cH:7][c:8]([C:12](=[O:13])[c:14]3[cH:15][c:16]([NH:20][C:21](=[O:22])[c:23]4[cH:24][n:25][n:26]([CH3:29])[c:27]4[Cl:28])[cH:17][cH:18][cH:19]3)[cH:9][cH:10][c:11]21>>[CH:2](=[C:3]1[C:4](=[O:30])[NH:5][c:6]2[cH:7][c:8]([C:12](=[O:13])[c:14]3[cH:15][c:16]([NH:20][C:21](=[O:22])[c:23]4[cH:24][n:25][n:26]([CH3:29])[c:27]4[Cl:28])[cH:17][cH:18][cH:19]3)[cH:9][cH:10][c:11]21)[NH:49][c:46]1[cH:45][cH:44][c:43]([CH2:42][CH2:41][N:36]2[CH2:37][CH2:38][CH2:39][CH2:40]2)[cH:48][cH:47]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8058HexaneHCID 8857Ethyl AcetateHCID 64870474-(2-(Pyrrolidin-1-yl)ethyl)anilineHCID 178481853HCID 178481853, compound

Product 1

HCID 1784818525-chloro-1-methyl-N-[3-[2-oxo-3-[[4-(2-pyrrolidin-1-ylethyl)anilino]methylidene]-1H-indole-6-carbonyl]phenyl]pyrazole-4-carboxamide

Sources & evidence

ORD record
ord-bed432e511c94ad5ad8f489012c212d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…