Dimethylformamide → 4-(8-(benzo[d][1,3]dioxol-5-ylmethyl)-8-aza-bicyclo[3.2.1]octan-3-ylamino)-6-chloro-1-(2,2,2-trifluoroethyl)quinazolin-2(1H)-one
Reaction equation
[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH:1]12[CH2:2][CH:3]([NH:9][c:10]3[n:11][c:12](=[O:26])[n:13]([CH2:21][C:22]([F:23])([F:24])[F:25])[c:14]4[cH:15][cH:16][c:17]([Cl:20])[cH:18][c:19]34)[CH2:4][CH:5]([CH2:6][CH2:7]1)[NH:8]2.[Cl:34][CH2:35][c:36]1[cH:37][c:38]2[c:39]([cH:43][cH:44]1)[O:40][CH2:41][O:42]2.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[CH:1]12[CH2:2][CH:3]([NH:9][c:10]3[n:11][c:12](=[O:26])[n:13]([CH2:21][C:22]([F:23])([F:24])[F:25])[c:14]4[cH:15][cH:16][c:17]([Cl:20])[cH:18][c:19]34)[CH2:4][CH:5]([CH2:6][CH2:7]1)[N:8]2[CH2:35][c:36]1[cH:37][c:38]2[c:39]([cH:43][cH:44]1)[O:40][CH2:41][O:42]2Participants
5
