Dimethylformamide → 2-Tert-butyl-5-dimethylamino-4-formyl-3(2H)-pyridazinone

Reaction equation

[C:6]([CH3:7])([CH3:8])([CH3:9])[n:10]1[n:11][cH:12][c:13]([N:17]([CH3:18])[CH3:19])[cH:14][c:15]1=[O:16].[O:20]=[CH:21][N:22]([CH3:23])[CH3:24].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[C:6]([CH3:7])([CH3:8])([CH3:9])[n:10]1[n:11][cH:12][c:13]([N:17]([CH3:18])[CH3:19])[c:14]([CH:21]=[O:20])[c:15]1=[O:16]

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 24813Phosphorus oxychloride

HCID 189189072-t-butyl-5-dimethylamino-3(2H)-pyridazinone

Product 1

HCID 189188952-Tert-butyl-5-dimethylamino-4-formyl-3(2H)-pyridazinone

Sources & evidence

ORD record: ord-280738fa6ea0409faf1dda769d166826
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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