Methylparaben → Methyl 4-(allyloxy)benzoate

HRID 2976

Reaction equation

HRID 2976 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[CH2:12](Br)[CH:13]=[CH2:14].C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[CH2:14]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:10][CH:11]=1)[CH:13]=[CH2:12]

Participants

5

Reactant 3

HCID 7456MethylparabenHCID 7841Allyl bromideHCID 11430Potassium Carbonate

Product 1

HCID 4645407Methyl 4-(allyloxy)benzoate

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 1.0 mmol of methyl 4-hydroxybenzoate, 2.0 mmol of allyl bromide, 5.0 mmol of K2CO3 in 2 mL of acetone was stirred for 16 h. Extraction provided methyl 4-allyloxybenzoate.

Workup

  1. extractionExtraction

Sources & evidence

ORD record
ord-136efa4c469642d7aa6076afa6f445aa
Source dataset
uspto-grants-1998_03
Patent number
US05731432

Linked notes

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