Hydrochloric Acid → 1-{2-[4-(2,4-Dichlorobenzyl)piperazin-1-yl]-2-oxoethyl}-3,3-diphenylpiperidin-2-one

HRID 298527

Reaction equation

HRID 298527 reaction equation
[CH2:40]([N:41]=[C:42]=[N:43][CH2:44][CH2:45][CH2:46][N:47]([CH3:48])[CH3:49])[CH3:50].[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[cH:11][cH:12][c:13]([Cl:15])[cH:14]1.[Cl:51][CH:52]([Cl:53])[CH3:54].[ClH:39].[O:16]=[C:17]1[N:18]([CH2:35][C:36](=[O:37])[OH:38])[CH2:19][CH2:20][CH2:21][C:22]1([c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[Cl:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][CH2:7][N:8]([C:36]([CH2:35][N:18]3[C:17](=[O:16])[C:22]([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)([c:29]4[cH:30][cH:31][cH:32][cH:33][cH:34]4)[CH2:21][CH2:20][CH2:19]3)=[O:37])[CH2:9][CH2:10]2)[cH:11][cH:12][c:13]([Cl:15])[cH:14]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 63651,1-DichloroethaneHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 4111791-(2,4-Dichlorobenzyl)piperazineHCID 673592802-(2-Oxo-3,3-diphenylpiperidin-1-yl)acetic acid

Product 1

HCID 452748211-{2-[4-(2,4-Dichlorobenzyl)piperazin-1-yl]-2-oxoethyl}-3,3-diphenylpiperidin-2-one

Sources & evidence

ORD record
ord-52849dc204e34ccb8775f5d6a87af97b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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