Bicarbonate Ion → Boc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid

Reaction equation

[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:1][O:2][C:3]([CH2:4][CH:5]([CH2:6][c:7]1[c:8]([F:15])[cH:9][c:10]([F:14])[c:11]([F:13])[cH:12]1)[NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24].[Li+:26].[Na+:32].[O-:28][C:29]([OH:30])=[O:31].[OH-:25].[OH2:27].[OH2:38]>>[O:2]=[C:3]([CH2:4][CH:5]([CH2:6][c:7]1[c:8]([F:15])[cH:9][c:10]([F:14])[c:11]([F:13])[cH:12]1)[NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[OH:24]

Participants

Reactant 7

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 962Water2×

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 666606403-Tert-butoxycarbonylamino-4-(2,4,5-trifluorophenyl)butanoic acid methyl ester

Product 1

Sources & evidence

ORD record: ord-fcff376db7d9438ca279ee654e44f737
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…