2,3-Dichlorobenzoic acid → 2,3-Dichloro-4-methylbenzoic acid

HRID 300452

Reaction equation

HRID 300452 reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][C:7]1([CH3:8])[CH2:9][CH2:10][CH2:11][C:12]([CH3:13])([CH3:14])[NH:15]1.[Cl:16][c:17]1[c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24][c:25]1[Cl:26].[I:27][CH3:28].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[CH3:1][c:24]1[cH:23][cH:22][c:18]([C:19](=[O:20])[OH:21])[c:17]([Cl:16])[c:25]1[Cl:26]

Participants

6

Reactant 5

HCID 57652,3-Dichlorobenzoic acidHCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 130352,2,6,6-TetramethylpiperidineHCID 178418339Butyllithium

Product 1

HCID 534304632,3-Dichloro-4-methylbenzoic acid

Sources & evidence

ORD record
ord-4e935a90810641f4901ed22b167b01ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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