1-Piperidinecarboxaldehyde → 5-Bromo-2-fluoro-3-pyridinecarboxaldehyde

HRID 302484

Reaction equation

HRID 302484 reaction equation
[Br:19][c:20]1[cH:21][cH:22][c:23]([F:26])[n:24][cH:25]1.[CH3:28][CH:29]([N-:30][CH:31]([CH3:32])[CH3:33])[CH3:34].[CH:35](=[O:36])[N:37]1[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]1.[Li+:27].[nH:1]1[c:2]2[c:3]([cH:4][cH:5][cH:6][cH:7]2)[cH:8][c:9]1-[c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15][cH:16]2)[nH:17][n:18]1>>[Br:19][c:20]1[cH:21][c:22]([CH:35]=[O:36])[c:23]([F:26])[n:24][cH:25]1

Participants

6

Reactant 5

HCID 174291-PiperidinecarboxaldehydeHCID 28486Lithium ionHCID 27831685-Bromo-2-fluoropyridineHCID 5062348DiisopropylamideHCID 178420010HCID 178420010, compound

Product 1

HCID 454801925-Bromo-2-fluoro-3-pyridinecarboxaldehyde

Sources & evidence

ORD record
ord-7171cb08bb2b457da9f65451ddd7f226
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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