Water → 1-Chloro-4-(3-methylpiperazin-1-yl)pyrido[3,4-d]pyridazine

HRID 305257

Reaction equation

HRID 305257 reaction equation
[CH3:13][CH:14]1[NH:15][CH2:16][CH2:17][NH:18][CH2:19]1.[CH3:20][N:21]1[CH2:22][CH2:23][CH2:24][C:25]1=[O:26].[Cl:1][c:2]1[c:3]2[c:4]([c:5]([Cl:8])[n:6][n:7]1)[cH:9][n:10][cH:11][cH:12]2.[OH2:27]>>[Cl:1][c:2]1[c:3]2[c:4]([c:5]([N:18]3[CH2:17][CH2:16][NH:15][CH:14]([CH3:13])[CH2:19]3)[n:6][n:7]1)[cH:9][n:10][cH:11][cH:12]2

Participants

5

Reactant 4

HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 660572-MethylpiperazineHCID 122244971,4-Dichloropyrido[4,3-d]pyridazine

Product 1

HCID 765851571-Chloro-4-(3-methylpiperazin-1-yl)pyrido[3,4-d]pyridazine

Sources & evidence

ORD record
ord-f6f9fc3b7f624461ab6d7fb0cfb67ba9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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