Phthalimide → 2-[(3-Chloropyrazin-2-yl)-quinolin-7-ylmethyl]-isoindole-1,3-dione

HRID 306515

Reaction equation

HRID 306515 reaction equation
[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[Cl:1][c:2]1[c:3]([CH:8]([OH:9])[c:10]2[cH:11][cH:12][c:13]3[cH:14][cH:15][cH:16][n:17][c:18]3[cH:19]2)[n:4][cH:5][cH:6][n:7]1.[O:20]=[C:21]1[NH:22][C:23](=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]21.[O:31]=[C:32]([O:33][CH:34]([CH3:35])[CH3:36])[N:37]=[N:38][C:39]([O:40][CH:41]([CH3:42])[CH3:43])=[O:44]>>[Cl:1][c:2]1[c:3]([CH:8]([c:10]2[cH:11][cH:12][c:13]3[cH:14][cH:15][cH:16][n:17][c:18]3[cH:19]2)[N:22]2[C:21](=[O:20])[c:30]3[c:25]([cH:26][cH:27][cH:28][cH:29]3)[C:23]2=[O:24])[n:4][cH:5][cH:6][n:7]1

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 8028TetrahydrofuranHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 57680924(3-Chloropyrazin-2-yl)-quinolin-7-ylmethanol

Product 1

HCID 536290242-[(3-Chloropyrazin-2-yl)-quinolin-7-ylmethyl]-isoindole-1,3-dione

Sources & evidence

ORD record
ord-a25083e83dd64d528cdac37716181917
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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