Hydrochloric Acid → 2-Amino-4-[(3,5-dimethyl-pyridin-2-yl-methyl)-amino]-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

HRID 308130

Reaction equation

HRID 308130 reaction equation
[CH2:30]1[CH2:31][CH2:32][C:33]2=[N:38][CH2:37][CH2:36][CH2:35][N:34]2[CH2:39][CH2:40]1.[CH3:20][c:21]1[c:22]([CH2:28][NH2:29])[n:23][cH:24][c:25]([CH3:27])[cH:26]1.[CH3:41][O:42][CH2:43][CH2:44][O:45][CH3:46].[ClH:18].[ClH:19].[NH2:1][c:2]1[n:3][c:4](-[n:13]2[n:14][cH:15][cH:16][cH:17]2)[c:5]([C:11]#[N:12])[c:6]([S:8]([CH3:9])=[O:10])[n:7]1>>[NH2:1][c:2]1[n:3][c:4](-[n:13]2[n:14][cH:15][cH:16][cH:17]2)[c:5]([C:11]#[N:12])[c:6]([NH:29][CH2:28][c:22]2[c:21]([CH3:20])[cH:26][c:25]([CH3:27])[cH:24][n:23]2)[n:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 80711,2-DimethoxyethaneHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507412(3,5-Dimethylpyridin-2-yl)methanamineHCID 185075202-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

Product 1

HCID 185075012-Amino-4-[(3,5-dimethyl-pyridin-2-yl-methyl)-amino]-6-pyrazol-1-yl-pyrimidine-5-carbonitrile

Sources & evidence

ORD record
ord-12aea32bd7d44e44bc952b0f1b548698
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…