Ammonium → 4-(2-Butynyloxy)-6-(2,3-difluorophenoxy)pyrimidine

HRID 308873

Reaction equation

HRID 308873 reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cl-:28].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([O:8][CH2:9][C:10]#[C:11][CH3:12])[cH:7]1.[F:19][c:20]1[c:21]([OH:27])[cH:22][cH:23][cH:24][c:25]1[F:26].[K+:17].[K+:18].[NH4+:29]>>[c:2]1([O:27][c:21]2[c:20]([F:19])[c:25]([F:26])[cH:24][cH:23][cH:22]2)[n:3][cH:4][n:5][c:6]([O:8][CH2:9][C:10]#[C:11][CH3:12])[cH:7]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 808792,3-DifluorophenolHCID 121376024-(2-Butynyloxy)-6-chloropyrimidine

Product 1

HCID 225997294-(2-Butynyloxy)-6-(2,3-difluorophenoxy)pyrimidine

Sources & evidence

ORD record
ord-dda0565715d945ed87214c2203efd6da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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