Hydrochloric Acid → 2-Methyl-5-(4-o-tolyl-piperazin-1-ylmethyl)-pyrimidin-4-ylamine

HRID 311917

Reaction equation

HRID 311917 reaction equation
[C:12](=[O:13])([O-:14])[O-:15].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:2][CH2:3][c:4]1[c:5]([NH2:11])[n:6][c:7]([CH3:10])[n:8][cH:9]1.[ClH:18].[ClH:19].[ClH:1].[K+:16].[K+:17].[c:20]1([CH3:32])[c:21]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:22][cH:23][cH:24][cH:25]1>>[CH2:3]([c:4]1[c:5]([NH2:11])[n:6][c:7]([CH3:10])[n:8][cH:9]1)[N:29]1[CH2:28][CH2:27][N:26]([c:21]2[c:20]([CH3:32])[cH:25][cH:24][cH:23][cH:22]2)[CH2:31][CH2:30]1

Participants

7

Reactant 6

HCID 313Hydrochloric Acid3×HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 919652-MeppHCID 4212454-Amino-5-(chloromethyl)-2-methylpyrimidine

Product 1

HCID 214736052-Methyl-5-(4-o-tolyl-piperazin-1-ylmethyl)-pyrimidin-4-ylamine

Sources & evidence

ORD record
ord-5ea394469b2c4398bebb092b1054bb98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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