Tetrahydrofuran → 2-(2-Hydroxyethyl)-3-hydroxymethyl-5-pyridin-2-yl-4-quinolin-4-yl-pyrazole

HRID 316133

Reaction equation

HRID 316133 reaction equation
[Al+3:28].[H-:27].[H-:30].[H-:31].[H-:32].[Li+:29].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1.[n:1]1[c:2](-[c:7]2[n:8][n:9]3[c:10]([c:16]2-[c:17]2[cH:18][cH:19][n:20][c:21]4[cH:22][cH:23][cH:24][cH:25][c:26]24)[C:11](=[O:15])[O:12][CH2:13][CH2:14]3)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2](-[c:7]2[n:8][n:9]([CH2:14][CH2:13][OH:12])[c:10]([CH2:11][OH:15])[c:16]2-[c:17]2[cH:18][cH:19][n:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)[cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 99241292-Pyridin-2-yl-3-quinolin-4-yl-pyrazolo[5,1-c]morpholin-4-one

Product 1

HCID 219926122-(2-Hydroxyethyl)-3-hydroxymethyl-5-pyridin-2-yl-4-quinolin-4-yl-pyrazole

Sources & evidence

ORD record
ord-6003addba8484c3cb6541d0e9b2d33f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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