Dimethyl Sulfoxide → Biphenyl-2-ylcarbamic Acid 1-[2-(4-Formylphenylcarbamoyl)ethyl]piperidin-4-yl Ester

HRID 318164

Reaction equation

HRID 318164 reaction equation
[CH3:78][S:79]([CH3:80])=[O:81].[CH:69]([N:70]([CH2:71][CH3:72])[CH:73]([CH3:74])[CH3:75])([CH3:76])[CH3:77].[Cl:92][CH2:93][Cl:94].[NH2:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([NH:9][C:10](=[O:11])[CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([O:20][C:21]([NH:22][c:23]3[c:24](-[c:29]4[cH:30][cH:31][cH:32][cH:33][cH:34]4)[cH:25][cH:26][cH:27][cH:28]3)=[O:35])[CH2:18][CH2:19]2)[cH:7][cH:8]1.[NH2:36][c:37]1[cH:38][cH:39][c:40]([CH2:41][OH:42])[cH:43][cH:44]1.[P-:45]([F:46])([F:47])([F:48])([F:49])([F:50])[F:51].[S:88](=[O:89])(=[O:90])=[O:91].[n:52]1([O:53][C:54]([N:55]([CH3:56])[CH3:57])=[N+:58]([CH3:59])[CH3:60])[c:61]2[n:62][cH:63][cH:64][cH:65][c:66]2[n:67][n:68]1.[n:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1>>[CH:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][C:10](=[O:11])[CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([O:20][C:21]([NH:22][c:23]3[c:24](-[c:29]4[cH:30][cH:31][cH:32][cH:33][cH:34]4)[cH:25][cH:26][cH:27][cH:28]3)=[O:35])[CH2:18][CH2:19]2)[cH:7][cH:8]1)=[O:42]

Participants

10

Reactant 9

HCID 679Dimethyl SulfoxideHCID 1049PyridineHCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 24682Sulfur trioxideHCID 693314-Aminobenzyl alcoholHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 59340340Biphenyl-2-ylcarbamic Acid 1-[2-(4-Aminomethylphenylcarbamoyl)ethyl]piperidin-4-yl Ester

Product 1

HCID 59340337Biphenyl-2-ylcarbamic Acid 1-[2-(4-Formylphenylcarbamoyl)ethyl]piperidin-4-yl Ester

Sources & evidence

ORD record
ord-e52a5a1078454ae7a22b0334ce5dfc9e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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