Piperazine → 2-Nitropyridine

HRID 319018

Reaction equation

HRID 319018 reaction equation
[Br:19][c:20]1[cH:21][n:22][cH:23][c:24]([N+:25]([O-:26])=[O:27])[cH:28]1.[Br:29][c:30]1[c:31]([O:32][CH3:33])[n:34][cH:35][c:36]([N+:37]([O-:38])=[O:39])[cH:40]1.[Br:41][c:42]1[cH:43][c:44]([N+:45]([O-:46])=[O:47])[cH:48][cH:49][n:50]1.[Br:51][c:52]1[cH:53][c:54]([N+:58](=[O:59])[O-:60])[n:55][cH:56][cH:57]1.[Br:61][c:62]1[c:63]([O:64][CH3:65])[cH:66][n:67][c:68]([N+:69]([O-:70])=[O:71])[cH:72]1.[CH2:13]1[NH:14][CH2:15][CH2:16][NH:17][CH2:18]1.[N:1]1([c:2]2[cH:3][cH:4][cH:5][cH:6][n:7]2)[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]1>>[cH:52]1[cH:53][c:54]([N+:58](=[O:59])[O-:60])[n:55][cH:56][cH:57]1

Participants

8

Reactant 7

HCID 4837PiperazineHCID 944591-(2-Pyridyl)piperazineHCID 2430152-Bromo-4-nitropyridineHCID 27628983-Bromo-5-nitropyridineHCID 215844513-Bromo-2-methoxy-5-nitropyridineHCID 234368574-Bromo-2-nitropyridineHCID 687099284-Bromo-5-methoxy-2-nitropyridine

Product 1

HCID 269982-Nitropyridine

Sources & evidence

ORD record
ord-8095ebf190f74285b2c261680072e3cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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