Hydrochloric Acid → 2-(3-Chloro-4-methanesulfonyl-phenyl)-3-(3-oxo-cyclopentyl)-propionic acid methyl ester

Reaction equation

[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]1[CH2:7][C:8]2([CH2:9][CH2:10]1)[O:11][CH2:15][CH2:14][CH2:13][O:12]2)[c:16]1[cH:17][c:18]([Cl:26])[c:19]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:20][cH:21]1)=[O:27].[ClH:28].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[CH3:1][O:2][C:3]([CH:4]([CH2:5][CH:6]1[CH2:7][C:8](=[O:11])[CH2:9][CH2:10]1)[c:16]1[cH:17][c:18]([Cl:26])[c:19]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:20][cH:21]1)=[O:27]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 8028Tetrahydrofuran

HCID 674820872-(3-Chloro-4-methanesulfonyl-phenyl)-3-(6,10-dioxa-spiro[4.5]dec-2-yl)-propionic acid methyl ester

Product 1

HCID 674822472-(3-Chloro-4-methanesulfonyl-phenyl)-3-(3-oxo-cyclopentyl)-propionic acid methyl ester

Sources & evidence

ORD record: ord-d25ddf47133248ce959c2f2836569477
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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