Acetone → N-(1-methyl-2-pyrrolidinyl-methyl)-2-methyl-5-sulfamoyl-2,3-dihydrobenzofuran-7-carboxamide

HRID 320328

Reaction equation

HRID 320328 reaction equation
[C:18]([Cl:19])(=[O:20])[O:21][CH2:22][CH3:23].[CH3:1][CH:2]1[O:3][c:4]2[c:5]([cH:7][c:8]([S:14]([NH2:15])(=[O:16])=[O:17])[cH:9][c:10]2[C:11](=[O:12])[OH:13])[CH2:6]1.[CH3:24][N:25]1[CH:26]([CH2:30][NH2:31])[CH2:27][CH2:28][CH2:29]1.[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[CH3:37][C:38](=[O:39])[CH3:40].[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47]>>[CH3:1][CH:2]1[O:3][c:4]2[c:5]([cH:7][c:8]([S:14]([NH2:15])(=[O:16])=[O:17])[cH:9][c:10]2[C:11](=[O:13])[NH:31][CH2:30][CH:26]2[N:25]([CH3:24])[CH2:29][CH2:28][CH2:27]2)[CH2:6]1

Participants

7

Reactant 6

HCID 180AcetoneHCID 6228DimethylformamideHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 1173001-Methylpyrrolidine-2-methylamineHCID 136908862-Methyl-5-sulfamoyl-2,3-dihydrobenzofuran-7-carboxylic acid

Product 1

HCID 13420590N-(1-methyl-2-pyrrolidinyl-methyl)-2-methyl-5-sulfamoyl-2,3-dihydrobenzofuran-7-carboxamide

Sources & evidence

ORD record
ord-afa81135132c4ca493b85963feed8776
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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