Phosphorus oxychloride → 2-Chloro-5-(methylthio)-1,3-dinitrobenzene
Reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[C:6](O)=[C:5]([N+:13]([O-:15])=[O:14])[CH:4]=1.P(Cl)(Cl)([Cl:18])=O>CN(C)C=O>[Cl:18][C:6]1[C:7]([N+:9]([O-:11])=[O:10])=[CH:8][C:3]([S:2][CH3:1])=[CH:4][C:5]=1[N+:13]([O-:15])=[O:14]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 4-(methylthio)-2,6-dinitrophenol (1 g.), phosphorus oxychloride (7.5 ml.), and dimethylformamide (1 ml.) is heated at 90°-100° C. for four hours. The cooled reaction mixture is poured into ice-water. The resulting product is collected by filtration.
Workup
- temperatureis heated at 90°-100° C. for four hours
- customThe cooled reaction mixture
- filtrationThe resulting product is collected by filtration
Sources & evidence
- ORD record
- ord-06eda12b8ab249d1a1886d0b9415fd24
- Source dataset
- uspto-grants-1977_04
- Patent number
- US04017538
Reaction notes
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