Hydrochloric Acid → N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

HRID 329757

Reaction equation

HRID 329757 reaction equation
C[Al](C)C.Cl.[CH2:6]([O:8][NH2:9])[CH3:7].[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31](OC)=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1.Cl>C(Cl)Cl>[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31]([NH:9][O:8][CH2:6][CH3:7])=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 52997Sulfometuron-methylHCID 76850O-ethylhydroxylamine hydrochlorideHCID 16682925Trimethylaluminum

Product 1

HCID 19871558N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To 2.9 g of trimethylaluminum in 100 ml of methylene chloride is added 2.0 g of ethoxyamine hydrochloride with stirring at ambient temperature. To this mixture is added 3.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and the solution is refluxed for 18 hours. The reaction mixture is treated with aqueous hydrochloric acid and the resulting precipitated product is purified by chromatography.

Workup

  1. temperaturethe solution is refluxed for 18 hours
  2. customthe resulting precipitated product
  3. customis purified by chromatography

Sources & evidence

ORD record
ord-a3ef8abf81d14e7cb104d6a293d44aef
Source dataset
uspto-grants-1990_01
Patent number
US04892946

Linked notes

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