Water → HCID 70200688, compound

HRID 342416

Reaction equation

HRID 342416 reaction equation
Br[CH2:2][C:3]1[O:7][C:6]2[C:8]([N+:12]([O-:14])=[O:13])=[CH:9][CH:10]=[CH:11][C:5]=2[CH:4]=1.[SH:15][CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18].C(=O)([O-])[O-].[K+].[K+].O>CN(C)C=O>[CH2:20]([O:19][C:17]([CH2:16][S:15][CH2:2][C:3]1[O:7][C:6]2[C:8]([N+:12]([O-:14])=[O:13])=[CH:9][CH:10]=[CH:11][C:5]=2[CH:4]=1)=[O:18])[CH3:21]

Participants

6

Reactant 4

HCID 962WaterHCID 11430Potassium CarbonateHCID 12185Ethyl ThioglycolateHCID 702014072-Bromomethyl-7-nitrobenzo[b]furan

Product 1

HCID 70200688HCID 70200688, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 2-bromomethyl-7-nitrobenzo[b]furan (512 mg), ethyl mercaptoacetate (0.24 ml) and potassium carbonate (552 mg) in N,N-dimethylformamide (4 ml) was stirred at ambient temperature for 2 hours. To the reaction mixture was added cold water and the separated solid was collected, washed with water and dried to give 2-ethoxycarbonylmethylthiomethyl-7-nitrobenzo[b]furan (546 mg).

Workup

  1. customthe separated solid was collected
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-c97ab92142a54cd2a3d37fd60633a382
Source dataset
uspto-grants-1999_01
Patent number
US05858995

Linked notes

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