Salicylic Acid → 5-(2-Propylpentanoyl)Salicylic Acid

HRID 35510

Reaction equation

HRID 35510 reaction equation
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15](Cl)=[O:16])[CH2:12][CH3:13]>>[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15]([C:7]1[CH:8]=[C:2]([C:1]([OH:10])=[O:9])[C:3]([OH:4])=[CH:5][CH:6]=1)=[O:16])[CH2:12][CH3:13]

Participants

3

Reactant 2

HCID 338Salicylic AcidHCID 762402-Propylvaleryl chloride

Product 1

HCID 137487105-(2-Propylpentanoyl)Salicylic AcidYield 52%

Procedure

This compound is prepared by a Friedel-Crafts reaction from salicylic acid and 2-propylpentanoyl chloride. The acid yield is 52%. The recrystallization is done in petroleum ether. The melting point is 118° C.

Workup

  1. customThe recrystallization

Sources & evidence

ORD record
ord-6261f72d624144a1932153c5569dbb6b
Source dataset
uspto-grants-1988_08
Patent number
US04767750

Linked notes

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