Hydrochloric Acid → HCID 18940945, compound

HRID 356047

Reaction equation

HRID 356047 reaction equation
C(N=[N+]=[N-])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[N+:12]([C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][CH2:19][CH2:18]2)([O-:14])=[O:13].[NH2:24][C:25](N)=[O:26].[ClH:28]>CCOCC>[ClH:28].[N+:12]([C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([C:25](=[O:26])[NH:24][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1)[CH2:19][CH2:18]2)([O-:14])=[O:13]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 1176UreaHCID 199143-Pyridinecarbonyl AzideHCID 362195-Nitroindoline

Product 1

HCID 18940945HCID 18940945, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

This material was prepared from nicotinoyl azide (0.43 g, 2.9 mmol) and 5-nitroindoline (0.38 g, 2.3 mmol), and conversion of the precipitated urea to the salt using excess HCl in ether, following the procedure of Example 2. This gave the title compound (0.64 g, 76%) as a light yellow powder, m.p. 244°-7° C. (dec.).

Sources & evidence

ORD record
ord-aafc92b2637a4682a1f40d81e42fab24
Source dataset
uspto-grants-1998_11
Patent number
US05834494

Linked notes

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