1-Phenylpiperazine → HCID 19433570, compound

HRID 37368

Reaction equation

HRID 37368 reaction equation
[C:1]1([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13]([OH:23])(=[O:22])[C:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[CH2:15]>C(O)C>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:15][CH:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:13]([OH:23])=[O:22])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 70961-PhenylpiperazineHCID 68114Atropic acid

Product 1

HCID 19433570HCID 19433570, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-Phenylpiperazine and atropic acid in ethanol is heated under reflux for 18 h, cooled to room temperature, and evaporated in vacuo. The solid is triturated with acetone to give the title product.

Workup

  1. temperatureunder reflux for 18 h
  2. customevaporated in vacuo
  3. customThe solid is triturated with acetone

Sources & evidence

ORD record
ord-ddfe5d50e0a74f92b0510bc2dfbdf66c
Source dataset
uspto-grants-1995_05
Patent number
US05420278

Linked notes

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