p-Toluenesulfonic acid → 5-(2,3-Difluoro-4-hydroxyphenyl)-2-(6-hexyloxypyridin-3-yl)pyrimidine
Reaction equation
C1(C)C=CC(S(O)(=O)=O)=CC=1.C([O:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]2[CH:27]=[N:28][C:29]([C:32]3[CH:33]=[N:34][C:35]([O:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])=[CH:36][CH:37]=3)=[N:30][CH:31]=2)=[C:22]([F:45])[C:21]=1[F:46])C1C=CC=CC=1.[H][H]>C1COCC1.[Pd]>[F:45][C:22]1[C:21]([F:46])=[C:20]([OH:19])[CH:25]=[CH:24][C:23]=1[C:26]1[CH:31]=[N:30][C:29]([C:32]2[CH:33]=[N:34][C:35]([O:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44])=[CH:36][CH:37]=2)=[N:28][CH:27]=1Participants
6
