Retinoic Acid → 9-Cis-Retinoic Acid

HRID 43313

Reaction equation

HRID 43313 reaction equation
[CH3:1][C:2]1[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[C:3]=1/[CH:10]=[CH:11]/[C:12](/[CH3:22])=[CH:13]/[CH:14]=[CH:15]/[C:16](/[CH3:21])=[CH:17]/[C:18]([OH:20])=[O:19]>C(O)(C)C>[CH3:1][C:2]1[CH2:7][CH2:6][CH2:5][C:4]([CH3:8])([CH3:9])[C:3]=1/[CH:10]=[CH:11]/[C:12](/[CH3:22])=[CH:13]\[CH:14]=[CH:15]\[C:16](\[CH3:21])=[CH:17]\[C:18]([OH:20])=[O:19]

Participants

3

Reactant 1

HCID 444795Retinoic Acid

Product 1

HCID 4491719-Cis-Retinoic Acid

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The raw retinoic acid thus obtained was suspended in 235.5 g (300 ml) isopropanol (w=1.0) and refluxed.

Workup

  1. temperaturerefluxed

Sources & evidence

ORD record
ord-9801c11d98dc42678e03398f0533c4eb
Source dataset
uspto-grants-2013_09
Patent number
US08536373B2

Linked notes

Loading…