Carbon Dioxide → 3,5-Dimethyl-1,3-oxazolidin-2-one

HRID 457003

Reaction equation

HRID 457003 reaction equation
Cl[CH2:2][CH:3](Cl)[CH3:4].[CH3:6][NH2:7].[C:8](=[O:10])=[O:9]>>[CH3:6][N:7]1[CH:3]([CH3:4])[CH2:2][O:9][C:8]1=[O:10].[CH3:6][N:7]1[CH2:2][CH:3]([CH3:4])[O:9][C:8]1=[O:10]

Participants

5

Reactant 3

HCID 280Carbon DioxideHCID 6329MethylamineHCID 65641,2-Dichloropropane

Product 2

HCID 134324433,5-Dimethyl-1,3-oxazolidin-2-oneHCID 135479893,4-Dimethyl-1,3-oxazolidin-2-one

Conditions

Temperature
160 °C

Procedure

1.10 g of 1,2-dichloropropane and 7.18 g of a 40% methylamine aqueous solution were charged in a 20 ml pressure vessel made of SUS316 and 2.11 g of a carbon dioxide gas was absorbed under a pressure of about 0.5 MPa, followed by heating at 160° C. for 4 hours. As a result, 3,4-dimethyl-1,3-oxazolidin-2-one and 3,5-dimethyl-1,3-oxazolidin-2-one were obtained in a total yield of 64% and 1,3,4-trimethylimidazolidin-2-one was obtained in a 23% yield.

Workup

  1. customwas absorbed under a pressure of about 0.5 MPa

Sources & evidence

ORD record
ord-0843a39209e84f0b9637debc40425a93
Source dataset
uspto-grants-2007_03
Patent number
US07186844B2

Linked notes

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