Triphenylphosphine → HCID 54050117, compound

HRID 458875

Reaction equation

HRID 458875 reaction equation
O[CH2:2][CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:16])[CH:8]=[CH:9][C:10]1[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH:36](=[C:43]1[S:47][C:46](=[O:48])[NH:45][C:44]1=[O:49])[C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1.C(OC(N=NC(OCC)=O)=O)C>C1COCC1>[CH:36](=[C:43]1[S:47][C:46](=[O:48])[N:45]([CH2:2][CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:16])[CH:8]=[CH:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)[C:44]1=[O:49])[C:37]1[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=1

Participants

6

Reactant 4

HCID 11776TriphenylphosphineHCID 1991545-Benzylidene-2,4-thiazolidinedioneHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 53817888HCID 53817888, compound

Product 1

HCID 54050117HCID 54050117, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Batch size: 13.5 g (61.3 mmol) N-(4-hydroxybutyl)-3-pyridin-3-yl-acrylamide, 16.1 g (61.3 mmol) triphenylphosphine, 12.6 g (61.3 mmol) 5-benzyliden-thiazolidin-2,4-dione and 9.7 ml (61.3 mmol) azodicarboxylic acid diethyl ester in 250 ml THF.

Sources & evidence

ORD record
ord-062f4f3536a740c0a50d0dac2f574d19
Source dataset
uspto-grants-2007_03
Patent number
US07192967B1

Linked notes

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