tert-Butyl hydroperoxide → 2-Hexyloxirane

Temperature

90 °C

In this example, the liquid phase epoxidation of an olefinic compound with an organic hydroperoxide was carried out in the presence of a catalytic amount of a boron containing substance in accordance with the instant invention. A 250 ml. flask equipped with a stirrer, thermometer, reflux condenser and dropping funnel was charged with 48 g. octene-1 L and 1 g. tungsten boride (WB). The charged mixture was heated to 90° C and 90% tertiary butyl hydroperoxide was added dropwise until a total of 25 g. had been added. The reaction mixture was then heated at reflux (108°-110° C) for 220 minutes with stirring. The heated mixture was allowed to cool and then the crude reaction product was analyzed. The analysis indicated a 36% yield of octene oxide based on the amount of charged hydroperoxide. The crude reaction product was filtered by conventional methods and the resulting filtrate was analyzed for metal content by atomic absorption analysis. No metals were detected in the filtrate.

1. customflask equipped with a stirrer
2. temperaturethermometer, reflux condenser
3. additionwas charged with 48 g
4. additionhad been added
5. temperatureThe reaction mixture was then heated
6. temperatureat reflux (108°-110° C) for 220 minutes
7. temperatureto cool
8. customthe crude reaction product

ORD record

ord-db25b04722aa4c03b2e6177eb3042139

Source dataset

uspto-grants-1977_12

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04065476