Acetonitrile → 7-(N,N-dipropylamino)-5,6,7,8-tetrahydronaphtho(2,3-b)dihydro-2,3-furan
Reaction equation
[CH2:1](I)[CH2:2][CH3:3].[C:5](=O)([O-])[O-].[K+].[K+].Cl.[NH2:12][CH:13]1[CH2:25][C:24]2[C:16](=[CH:17][C:18]3[CH2:22][CH2:21][O:20][C:19]=3[CH:23]=2)[CH2:15][CH2:14]1.[C:26](#N)[CH3:27]>>[CH2:1]([N:12]([CH:13]1[CH2:25][C:24]2[C:16](=[CH:17][C:18]3[CH2:22][CH2:21][O:20][C:19]=3[CH:23]=2)[CH2:15][CH2:14]1)[CH2:5][CH2:26][CH3:27])[CH2:2][CH3:3]Participants
5
Procedure
13.4 g of propyl iodide and 11 g of potassium carbonate are added to 1.5 g of the compound of Example 2 dissolved in 10 ml of acetonitrile.
Sources & evidence
- ORD record
- ord-bd2a45f50e4d41ec95e6b7aa583f43de
- Source dataset
- uspto-grants-1989_12
- Patent number
- US04885373
Reaction notes
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