Methylamine → HCID 19836622, compound
Reaction equation
[CH3:1][C:2]1([CH3:13])[CH2:4][N:3]1[P:5](Br)([N:7]1[CH2:9][C:8]1([CH3:11])[CH3:10])=[S:6].[CH3:14][NH2:15]>C1COCC1>[CH3:1][C:2]1([CH3:13])[CH2:4][N:3]1[P:5]([N:7]1[CH2:9][C:8]1([CH3:11])[CH3:10])(=[S:6])[NH:15][CH3:14]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
In a similar manner 0.025 moles of P,P-bis(2,2-dimethyl-1-aziridinyl)thiophosphinic bromide in about 170 milliliters of THF, prepared in accordance with Example 1, is saturated with an excess of gaseous methylamine, kept overnight at 4° C., filtered, concentrated on a rotary evaporator at room temperature, and vacuum distilled to provide about 65% yield of P,P-bis(2,2-dimethyl-1-aziridinyl)-N methylthiophosphinic amide.
Workup
- filtrationfiltered
- concentrationconcentrated on a rotary evaporator at room temperature
- distillationvacuum distilled
Sources & evidence
- ORD record
- ord-213cc3ff20f0414b9f45dcbb8e927f15
- Source dataset
- uspto-grants-1989_12
- Patent number
- US04886790
Reaction notes
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