Benzaldehyde → Chalcone

Reaction equation

[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)(=O)[CH3:10]>>[CH:15]1[CH:16]=[CH:17][C:12](/[CH:9]=[CH:10]/[C:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[O:8])=[CH:13][CH:14]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 7410Acetophenone

Product 1

HCID 637760Chalcone

Procedure

The compound was not synthesised according to the procedure of Example 1. Instead, an aldol condensation of equimolar amounts of benzaldehyde and acetophenone were first of all carried out to give 1,3-diphenylpropenone:

Workup

customThe compound was not synthesised

Sources & evidence

ORD record: ord-db9c16c672d84d3b9dd606a995ae13f0
Source dataset: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06653508B2

Reaction notes

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