Hydrochloric Acid → 2-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,5-dione

HRID 505476

Reaction equation

HRID 505476 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]=[C:11]=[S:12])=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[O-:14][Mn](=O)(=O)=O.[K+].[CH2:20]([N:22]=[C:23]=[O:24])[CH3:21]>C1COCC1>[CH2:20]([N:22]1[C:23](=[O:24])[N:10]([C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=2)[C:11](=[O:14])[S:12]1)[CH3:21]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 8022Ethyl isocyanateHCID 75044Benzene, 1-isothiocyanato-4-nitro-HCID 516875Potassium Permanganate

Product 1

HCID 65391732-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,5-dione

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Reagents: 4-nitrophenyl isothiocyanate (1.17 g, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), ethyl isocyanate (0.51 ml, 6.5 mmol) in THF.

Sources & evidence

ORD record
ord-a4e103d00cc74487835c37af8c4f552d
Source dataset
uspto-grants-2010_08
Patent number
US07781463B2

Linked notes

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